2 series of cationic lipids were designed, synthesized and purified. The prepared 40 compounds, most of which are new compounds, were all characterized correct by IR, ~1H NMR, ~(13)C NMR, HRMS or MS, which can be used for gene delivery.

• 本论文设计了2类基因载体阳离子类脂,合成、提纯了计40个化合物,其中大部分为新化合物,全部产品经过IR,~1H NMR,~(13)C NMR,HRMS或MS表征结构正确,纯度符合转染要求。