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- Our data show that 5 aza CdR may inhibit tumor growth by reactivating growth regulatory genes silenced by de novo methylation. 5 aza CdR有肯定的抑瘤作用 ,其抑瘤作用的可能机理主要是通过p16基因去甲基化解除转录抑制完成的。
- In SW1116 and Colo 320 cells, the expression of p16 INK4A and APC genes was markedly increased after treatment of 5 aza dC, although 5 aza dC treatment did not activate the expression of p21 WAF1 gene. 以 5 aza dC干预后 ,p1 6 INK4A和APC表达增强 ,且不同的结肠癌细胞系表达增强最明显时 5 aza dC干预的时间与浓度不同。
- METHODS: Human breast cancer cell line MCF 7, human gastric cancer cell line BGC 823, human prostate cancer cell line DU 145, and human colon cancer cell line HT 29 were treated with 5 Aza CdR. 方法:用5-Aza-CdR作用人乳腺癌细胞系MCF-7、人胃癌细胞系BGC-823、人的前列腺癌细胞系DU-145和人结肠癌细胞系HT-29。
- Effect of the demethylating agent 5,Aza,2＇,deoxycytidine on the growth of human gastric carcinoma cell lines. 去甲基化剂5-氮杂-2’-脱氧胞苷对胃癌细胞生物学行为的影响
- If you subtract 3 from 5, you get 2. 五减去三就得二。
- These fish vary in weight from 3 lb to 5 lb. 这些鱼的重量从3磅到5磅不等。
- The going rate for freelance work is 5 an hour. 自由职业者的现行酬金是每小时5英镑。
- Many children under 5 go to nursery school. 5岁以下的许多儿童都上幼儿园。
- Meals average out at 5 per head. 膳食平均每人5英镑。
- Children under 5 can travel for nothing. 5岁以下儿童可免付旅费。
- Even the cheapest was priced at 5. 即使最便宜的也标价5英镑。
- The liquid was 5 litres in volume. 该液体的体积为5升。
- The ratios of 1 to 5 and 20 to 100 are the same. 1与5之比和20与100之比相同。
- The difference between 5 and 7 is 2. 五和七之间的差额是二。
- The winning time was 1 minute 5 seconds. 获胜的时间是1分零5秒。
- I found a 5 note on the pavement. 我在人行道上捡到了一张5英镑的纸币。
- He is 5 centimeters taller than her. 他比她高5公分。
- He is 5 centimetres taller than her. 他比她高5公分。
- He made an offer of$5 for the old bike. 他出价5美元买这辆旧自行车。
- She got a rake-off of 5 per cent from the deal. 她从这笔交易中获得百分之五的回扣。
