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- Construction and Expression of Anti human Gastric Cancer mAb 3H11 Fab. 抗胃癌单抗3H11可变区氨基端序列对抗体活性的影响
- Meanwhile, anti human BPI polycolonal antibodies or monoclonal antibodies increased the binding ability of porcine BPI to endotoxin. 同时抗人BPI多克隆抗体和单克隆抗体可增加猪源BPI的结合内毒素活性。
- Study of Purification of Recombinant Human Erythropoietin Produced with FBSFree Medium. 无血清培养基生产重组人红细胞生成素的纯化。
- Goat anti human IgG Fab antibody affinity chromatography column was prepared and the Fab supernant was purified. 制备羊抗人IgGFab抗体亲和层析柱、纯化Fab片段。
- BACKGROUND: Recombinant human erythropoietin is commonly used for treatment of anaemia. 背景：重组体人红细胞生成素通常用于治疗贫血。
- Amifostine(AMF)was used alone(4/12)or combined with recombinant human erythropoietin(rh-EPO)(8/12)in 12 MDS patients. 采用单用AMF或联合红细胞生成素(rhEPO)治疗12例MDS患者,其中8位高龄患者采用AMF联合rhEPO治疗,4例单用AMF治疗。
- Objective:To obtain human mouse chimeric Fab fragment of the anti human small cell lung cancer mAb 2F7 by means of engineering antibody. 目的 :通过基因工程抗体改造获得具有与人小细胞肺癌有特异性反应的人 鼠嵌合抗体 2F7Fab片段。
- METHODS: The C5aR expressions on ERM tissue and cultured RPE cells were detected by ABC immunohistochemical staining with mouse anti human C5aR mcAbs. 另取新鲜人眼球 ,常规分离、培养人RPE细胞。 以小鼠抗人C5aR单克隆抗体作为检测抗体 ,对PVR患者的ERM组织及培养的人RPE细胞做细胞免疫化学ABC染色 ,检测C5aR的表达。
- Objective To prepare monoclonal antibody (McAb) against reconbinant human erythropoietin (rhEPO) and identify the biological features of the McAb. 目的研制特异性识别人促红细胞生成素的单克隆抗体，并对其生物学特性作出初步鉴定。
- Methods Broth culture was used to observe the changes of bactericidal rate of porcine BPI with or without anti human BPI antibody. 方法 采用肉汤培养法测定BPI在有或无抗人BPI抗体存在情况下猪源BPI对大肠杆菌J5的杀菌率变化 ;
- OBJECTIVE This article introduces a method to study the bacterial endotoxin test for detecting pyrogen in recombinant human erythropoietin injection. 目的本文介绍了一种重组人红细胞生成素注射液的细菌内毒素检查法。
- RESULTS Recombinant human erythropoietin injection in 150-fold dilution had no inerference to the bacterial endotoxin test. 结果重组人红细胞生成素注射液稀释150倍对细菌内毒素检查法无干扰。
- Anti human BPI polycolonal antibodies or monoclonal antibodies not only increase the bactericidal activity, but also increase the binding activity of porcine BPI to endotoxin. 抗人BPI多抗或单抗不仅能增加猪源BPI的杀菌活性 ,而且能增加其结合内毒素活性
- Unlike many biotechnology companies, 3SBio is profitable, largely because of its key product, EPIAO, an injectable recombinant human erythropoietin. 同许多生物技术公司不同的是，三生制药是盈利的，这主要是因为该公司的核心产品益比奥（重组人红细胞生成素）。
- Methods Anti human bladder carcinoma cell line BIU 87 monoclonal antibody BDI 1 was labelled with technetium 99m by direct mercaptoethanol reducing method. 方法采用抗人膀胱癌单克隆抗体BDI－1通过2－巯基乙醇直接还原法标记99mTc（99mTc）制备了99mTc－BDI－1。
- Mcnabon LP,Dawborn JK.Experience with low dose intranvenous and subcutaneous administration of recombinant human erythropoietin[J].Am J Nephol,1990,10(3):404. 吴俊;袁志忠;叶朝阳;等.;大剂量重组人红细胞生成素治疗尿毒症贫血的疗效观察[J]
- Results 98% purity was reached through 14F7 monoclonal antibody column, and 95% purity was gained after goat anti human Fab fragment column. But yield ratio of the two affinity columns was low, being 35% and 55%, respectively. 结果3种纯化方法中,14F7单克隆抗体柱纯化的Fab抗体的纯度达98%25左右,Fab抗体柱纯化的Fab抗体的纯度为95%25,但这两种亲和柱的目的蛋白收率都不高,分别为35%25、55%25。
- The results of detection of specific IgG4 in sera of 173 cerebral cysticercosis patients by dip test using gold labeled anti human IgG4 monoclonal antibody(McAb) were reported and compared with the case CT and MR scans. 应用金标抗人IgG4 McAb 浸测试验检测173 例脑囊虫病患者血清中特异IgG4，并与其脑CT、MR影像分型进行对比分析。
- The company was able to produce a synthetic version of human erythropoietin (which boosts red blood cell production and commands a $5-billion market) that is more than twice as potent as the hormone brewed in hamster cells. 该公司能够制造人造样式的人类红血球生成素（可刺激红血球的生成，拥有50亿美元的市场），其效果要比从仓鼠细胞所产生的激素高出两倍以上。
- After anti human BPI polycolonal antibodies or monoclonal antibodies having no bactericidal activities were added, bactericidal rate of porcine BPI increased. But the antibody not against BPI had no such improving bactericidal activity. 抗人BPI多克隆抗体和单克隆抗体加入后 ,猪源BPI的杀菌活性不仅不降低 ,反而增加 ,而抗体本身并不具有杀菌性 ,非抗BPI抗体也无此效应 ;
