ASPM overexpression plays important role in the tumor cell proliferation, differentiation, and invasion/metastasis, probably via the downregulation of p27 and upregulation of stathmin.

• ASPM基因的过量表现在肿瘤的细胞增殖、细胞分化以及肿瘤侵犯与转移扮演著重要的角色。