Aaron Ciechanover, Avram Hershko and Irwin Rose together discovered ubiquitin-mediated proteolysis, a process where an enzyme system tags unwanted proteins with many molecules of the 76-amino acid residue protein ubiquitin.

• 泛素是一种含 76 个氨基酸的多肽,存在于除细菌外的许多不同组织和器官中,具有标记待降解蛋白质的作用。