Abstract: Hirudin is the potent antithrombotic factor found in nature.Hirulog is a dind of peptides designed by imitating hirudin.

• 文摘:水蛭素是迄今发现的最强的天然凝血酶抑制剂，水蛭肽是模仿水蛭素与凝血酶的相互作用机制而合成的肽类化合物。