Accumulated data have shown that there are persistent and low-grade inflammatory state in CKD, which presented by increased plasma pro-inflammatory cytokines and acute-phase reactants(C-reactive protein (CRP)).

• 大量证据表明，CKD患者普遍存在着持续低度的全身炎症反应，表现为循环中存在着高水平的促炎症细胞因子及其拮抗物，以及血清急性时相反应物质如C-反应蛋白(C-Reactive Protein，CRP)等。