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- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Some applications of phenotyping &genotyping of drug metabolizing enzymes are also introduced. 最后主要讨论了表型分型和基因分型在药物代谢酶研究中的一些应用。
- Objective: To review the effects of the active components of Chinese herbs on drug metabolizing enzymes. 目的:综述近年来中药有效成分对药物代谢酶的影响的研究进展。
- With the exception of drug metabolizing enzymes, drug receptors are another important kinds of proteins involved in drug response. 这些差异的产生是遗传因素与环境因素共同作用的结果，其中遗传因素为决定性因素。
- The activities of metabolizing enzymes were measured by spectrophotography, and hepatic function was determined by biochemical analyser. 结果彗星发生率染毒组显著高于对照组,肝细胞和血淋巴细胞彗星发生率显著相关。
- The enzymes involved in alcohol metabolism include mainly alcohol dehydrogenase(ADH), aldehyde dehydrogenase(ALDH) and cytochrome P450 2E1(CYP2E1), which all appear to be polymorphic. 体内参与乙醇代谢的酶主要有乙醇脱氢酶(ADH)、乙醛脱氢酶(ALDH)和细胞色素P450-2E1(CYP2E1)，它们均存在基因多态现象。
- The important enzymes for alcohol metabolism include alcohol dehydrogenase(ADH) and aldehyde dehydrogenase(ALDH) in human body. ALDH2 has the important role in the effect of aldehyde detoxification which is always the outcome in alcohol metabolism. 乙醇脱氢酶(alcohol dehydrogenase,ADH)和乙醛脱氢酶(aldehyde dehydrogenase,ALDH)是人体内酒精代谢的重要酶,而乙醛脱氢酶2在酒精代谢产物乙醛的解毒中起重要的作用。
- To investigate DNA damage of liver cells and lymphocytes of rats exposed to vinyl chloride (VC),to examine the activities of VC metabolizing enzymes including GST,CYP2E1,ADH,and ALDH, and to explore early sensitive indexes to detect damage induced by VC. [目的 ]研究氯乙烯 (VC)对大鼠肝细胞和外周血淋巴细胞DNA的损伤作用 ,及对VC代谢酶 [谷胱甘肽硫转移酶 (GST)、细胞色素P45 0 2E1(CYP2E1)、乙醇脱氢酶 (ADH)和乙醛脱氢酶 (ALDH) ]活性的影响 ; 探索VC所致损伤的早期敏感检测指标。
- This review is focused on two main types of markers of susceptibility to benzene-induced hematotoxicology, metabolizing enzymes, DNA repairing enzymes, their polymorphisms are also addressed. 介绍苯致血液毒性两大类主要的易感性标记物、代谢酶,DNA修复酶及其多态性;
- Methods:By immunohistochemical methods, we examined the expression pattern of major arachidonic acid metabolizing enzymes in 17 samples of Crohn;s disease with associated intestinal fistula. 方法:通过免疫组化考察花生四烯酸代谢的主要酶系在17例克罗恩病并发肠瘘的病变肠组织的表达情况。
- Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) play an important role in the in vivo alcohol metabolism together. 人体中的乙醇脱氢酶(alcohol dehydrogenase,ADH)及乙醛脱氢酶(aldehyde dehydrogenase,ALDH)在乙醇代谢过程中发挥着重要的作用。
- Effects of Cd on brain AChE and metabolic enzymes in tissues of T. Nilotics. 镉对罗非鱼脑AChE及组织中代谢酶的影响。
- Why alcohol boosts risk isn't known, but one of several theories is that a by-product of alcohol metabolism acts as a co-carcinogen. 饮酒增加这一风险的原因尚不得而知，但诸多理论之一解释为酒精代谢的副产物扮演了共同致癌物的角色。
- Objective: To promote the study of drug metabolic enzymes in clinical practice. 目的:为了促进药物代谢酶在临床上的深入研究。
- The latest study found that this is because these people lack a body could help more alcohol metabolism aldehyde dehydrogenase. 最新的研究发现，这是因为这些人身体内部更缺少一种可以帮助代谢酒精的乙醛脱氢酶。
- Drug metabolism determines several pharmacological and toxicological properties of pharmaceuticals and is catalyzed by drug metabolizing enzymes. 药物代谢是在代谢酶催化下完成的,它决定着药物的药理学和毒理学特性。
- The judge enjoined him from selling alcohol. 法官禁止他卖酒。
- OBJECTIVE To investigate the effect of Shengmai injection (SMI) on the drug metabolizing enzyme of liver in mice. 目的:观察生脉注射液(SMI)对小鼠肝药酶的影响。
- Drug metabolic enzymes are one of the major factors causing the variation of drug effects as well as toxicity in pa... 结论:药物代谢酶的认识和研究有助于临床合理用药和减少药物不良反应。
- Skin is one of the main extrahepatic metabolic organs and expresses many kinds of metabolic enzymes. 皮肤是肝外药物代谢的主要器官之一,有多种代谢酶表达。
