Allopurinol, a XO inhibitor can improve the unbalanced distribution of calcium in heart failure to make the [Ca2+]i recover to the normal level and enhance the myocardial contractility.

• 黄嘌呤氧化酶抑制剂别嘌呤醇能改善心衰心肌钙分布的不平衡状态,使细胞内钙水平恢复接近正常水平,增加心肌的收缩力。