Along with the prevalence of type 2 diabetes and the trend of population senility worldwide, the mechanism of insulin hyposecretion and insulin resistance to type 2 diabetes has become the focus of world.

• 摘要随着世界范围内2型糖尿病的流行与人口老龄化，以胰岛素分泌不足和伴胰岛素抵抗为主要致病机制的2型糖尿病已成为国内外研究热点。