Among the main changes are generalized atrophy of the retina and choroid, and degeneration at the point where the optic nerve leaves the eye and in the macular area (where the fovea is located).

• 在这些主要变化中，是普遍的视网膜和脉络膜萎缩，视神经，黄斑区（视网膜中心凹所在地）退行性变。