An HPLC method was described for the determination of cefaclor. The chromatographic conditions were column:C18; mobile phase:pH3.4 phosphate buffermethanol(71:29):detected at 254nm with acetanilide as internal standard.

• 以磷酸盐缓冲液（pH3.；4）－甲醇（71：29）为流动相在C18往上分离测定头孢克洛（CCL），检测波长254nm，乙酰苯胺作内标。