An animal model of fulminant hepatic failure induced by thioacetamide wasused and Evans blue extracted from brain tissue was taken as the index of blood-brainbarrier permeability.

• 采用硫代乙酰胺所致大鼠暴发性肝衰模型，以脑组织浸泡液中Evans蓝含量为血脑屏障通透性指标。