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- Andrographolide Denvatives 穿心莲内酯衍生物
- Methods: The andrographolide and dehyandrographolide were detemined by HPLC. 方法:采用高效液相色谱(HPLC)法对穿心莲软胶囊中有效成分穿心莲内酯和脱水穿心莲内酯进行含量检测。
- Objective: To observe effect and safety of andrographolide injection to infant acute adenopharyngitis. 目的:观察穿琥宁佐治小儿急性扁桃体炎的疗效与安全性。
- In this paper, the development of synthesis of andrographolide derivatives is summarized. 作者对穿心莲内酯衍生物的合成进行了综述。
- Andrographolide is one of the major diterpenoidal active constituents of traditional Chinese medicine. 摘要穿心莲内酯是中药穿心莲的主要二萜类活性成分之一。
- Conclusion The orally disintegrating tablets of andrographolide without irritate were more c... 结论穿心莲内酯口腔崩解片吸收好,起效快,刺激小,口感好,服用方便。
- Conclusion Andrographolide injection can be generally used in treating children viral enteritis clinically. 结论穿琥宁注射液能广泛用于小儿病毒性肠炎的临床治疗。
- OBJECTIVE To design and synthesize a series of andrographolide derivatives for anti-HIV activity test. 目的设计并合成异穿心莲内酯衍生物。
- Objective To prepare orally disintegrating tablets of andrographolide and establish a quality control standard. 目的探讨穿心莲内酯口腔崩解片的制备工艺并建立其质量标准。
- METHODS Gradient elution method was used to determine the content of andrographolide and dehydroandrographolide in Qinghuo Zhimai tablets. 方法:用梯度洗脱法测定清火栀麦片中穿心莲内酯和脱水穿心莲内酯的含量。
- OBJECTIVE To control the quality of Qinghuo Zhimai tablets by determine the content of andrographolide and chrysophanol dehydroandrographolide. 目的:通过测定穿心莲内酯和脱水穿心莲内酯的含量来控制清火栀麦片的质量。
- Methods: HPLC method was applied to analyze andrographolide and 14 deoxy 11, 12 didehydroandrographolide in the process. 方法:以HPLC法测定了烘干过程中不同处理条件下样品的穿心莲内酯和脱水穿心莲内酯的含量。
- Objective To observe the clinical effects of combined therapy of ganciclovir and andrographolide on the infectious mononucleosis. 目标观察更昔洛韦结合炎琥宁对传染性单核细胞增多症的疗效。
- It was dected that andrographolide had the action of anti-tumor in gastric cancer,liver cancer,lung cancer and breast cancer. 在抗肿瘤方面的研究发现穿心莲内酯具有抗胃癌、肝癌、肺癌、乳癌等多种肿瘤的作用。
- Orthogonal experiments were used to find the optimal extraction process of andrographolide by microwave and ultrasonic assisted extraction. 用正交法对微波和超声波辅助提取穿心莲内酯的工艺条件进行优化。
- Methods: Using the method of HPLC and andrographolide as target, the effects to the contents of andrographolide of different extracts were determined. 方法:以穿心莲内酯为考察指标,以HPLC法测定不同提取方法对穿心莲内酯含量及出膏率的影响。
- Andrographolide,a bicyclic diterpenoid lactone(C20H30O5),is one of principal components isolated from the traditional Chinese herb Andrographis paniculata. 穿心莲内酯为爵床科植物穿心莲中提取得到的二萜内酯类化合物,分子式为C20H30O5,是中药穿心莲的主要有效成分之一。
- Content : minimum 0.80 per cent of total amount of andrographolide (C 20 H 30 O 5 ) and dehydroandrographolide (C 20 H 28 O 4 ), calculated with reference to the dried drug. 本品按干燥品计算,含穿心莲内酯(C 20 H 30 O 5 )和脱水穿心莲内酯(C 20 H 28 O 4 )的总量不得少于0.;80%25。
- The utilization of thymosin, human Y-globum, levofloxacin, azithromycin,houttuyfonate, andrographolide, methylprednisolone had markedly grown and been used to treat SARS. 胸腺肽、人免,疫球蛋白、左氧氟沙星、阿奇霉素、鱼腥草、穿琥宁、甲泼尼龙用量显著增长,并常用于SARS治疗。
- Result: Andrographolide microcapsules, which were prepared by above method, were little dissolved in water and quickly released in pH (1.0) and pH (2.0) of solution. 结果:该法制备的穿心莲内酯微囊,在水中药物几乎没有溶出,而在酸性溶出介质中则可快速释放。