Angiogenesis is an early critical step in the tumorigensis, invasion and metastasis of EOC. Abnormally active angiogenesis and malformation of vessel structure are main characters in malignant solid tumors.

• 实体肿瘤的生长、转移离不开血管生成，异常活跃的血管生成和血管结构的异常是恶性实体肿瘤的主要特征。