Angiogenin undergoes nuclear translocation in endothelial cells where it accumulates in the nucleolus and stimulates rRNA transcription, which is essential for angiogenesis.

• 已知血管生成素在血管内皮细胞中进行核转移作用，在核仁中发生积累并刺激rRNA的转录，进而诱发内皮细胞的增殖促进血管发生。