Anti-mesiangial cell antibodies could directly interact with antigens located on mesangial cell membrane and form in situ immune complexes in renal mesangium.

• 结论 1.；部分抗肾小球系膜细胞抗体与抗DNA抗体无关，提示抗DNA抗体以外的直接针对肾小球系膜细胞的自身抗体可能在狼疮肾炎的发病中起一定作用。