Any drug development effort to combat neurodegenerative disorders will have to examine carefully whether such pivotal signaling molecules adversely affect untargeted cell populations.

• 任何对抗神经退化的新药物，其发展都必须经过仔细的检验，以确定这些重要的讯息分子不会对不属于目标的诸多细胞造成不良的影响。