Application site reactions in the fentanyl group (6.3%) were mild to moderately severe in all but one case.Mild erythema occurred in 53.8% of patients at 24 hours and resolved within four weeks.

• 吩坦尼组中，几乎只有一位病例的使用部位产生轻度到稍微严重的反应(6.；3%25)，有53