As receptor of protein C and activated protein C,EPCR is essential in activating the protein C,and it has anti-inflammatory and cytoprotection effect in sepsis through activated protein C.

• EPCR不仅在蛋白C活化过程中起重要作用,而且作为蛋白C及活化蛋白C的共同受体,EPCR在脓毒症中亦介导了活化蛋白C抗炎及细胞保护作用的发挥。