BK injection into Atreated rats hippocampus produce obviously memory lesion and drastic neuronal loss .

• BK注人Ap所致AD大鼠海马，可引起比Ap单独注人更加明显的行为学改变，神经元损害不仅见于注射部位及其周围，而且见于远离注射区的顶叶皮层。