Background and objective: HMGB1(high mobility group box-1),also known previously as HMG1,is a nonhistone nuclear protein identified over 30 years ago and the name simply derives from the fact that it runs fast in SDS-polyacrylamide gels.

• 研究背景和目的:高迁移率族蛋白B1(high mobility group box-1,HMGB1)曾称为HMG1,是30多年前发现的非组蛋白核蛋白,因其在凝胶电泳中泳动速度快而得名[1]。