Base on Darwinian evolution theory and rencent molecular evolution theory, positive selection may contribute to human brain evolution, and such progress may embed some impression on gene or genomic substitution pattern.

• 根据达尔文的进化理论及近代分子进化理论,人类大脑的进化必将受到达尔文正向选择的作用,而这种作用将在基因、基因组上留下踪迹。