Based on the physiology of bone remodeling, a mechanical-biological factor coupled computational model at Basic Multicellular Units (BMUs) level was put forward, which can describe the osteoporotic process of cancellous bond with time course.

• 根据骨重建的生理过程,在基本多细胞单位(BMUs)层次建立了一个力学因素和生物学因素耦联的,带有时间历程的松质骨骨质疏松过程计算模型。