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- ObjectiveTo investigate the possible mechanism of basil polysaccharide in inhibiting tumor metastasis. 目的：探讨罗勒多糖抗肿瘤侵袭转移作用的可能机制，为罗勒多糖的进一步开发与临床应用提供理论依据。
- AIM: To study the effect of basil polysaccharide on the rat model bearing NuTu-19 cells. 目的:探讨罗勒多糖对荷NuTu-19卵巢癌大鼠模型的作用。
- One hundred sixty-eight differently expressed genes were found in the tumor specimen dealed with basil polysaccharide. 罗勒多糖作用后,卵巢癌的基因表达谱发生了明显变化,应用表达谱芯片共筛选出168条差异表达基因。
- Basil polysaccharide may have multi-targets during the anti-cancer metastasis process. 罗勒多糖通过多个药效靶点抗肿瘤增殖及转移。
- Objective: To study the effect of basil polysaccharide (BP) on tumor cell metastasis and its mechanism through assays of intercellular communication and NK cytotoxicity. 目的:观察罗勒多糖对肿瘤细胞不同途径转移行为的影响,并从细胞间通讯功能的恢复以及体内NK细胞活性的变化两方面探讨其抗肿瘤转移的可能作用机制。
- Objective:To investigate the effect of basil polysaccharide on ovarian carcinoma and analyze the potential mechanism using gene expression microarray. 目的:观察中药罗勒多糖对卵巢癌生物学行为的影响,探讨其抗卵巢癌作用的可能机制。
- Basil polysaccharide may be a new anti-tumor drug and it has multi-targets. Gene expression microarray has huge advantage and value in the study of the drug target. 罗勒多糖可能是一种抗卵巢癌转移的新型中草药,它对卵巢癌显现的独特效果可能是多个药效靶点综合作用的结果,本研究也显示了表达谱芯片技术在药物效应靶点研究中的优势和价值。
- Methods Rat model bearing NuTu-19 cells was made and the changes of biology phenotype in tumor cells were observed after treatment with Basil polysaccharide for 50 days. 方法建立荷NuTu-19卵巢癌的大鼠模型及相应对照,用罗勒多糖治疗50天,处死大鼠,以腹水量、腹腔脏器转移程度积分判断各组肿瘤生长及转移情况。
- Methods: The rat model bearing NuTu; 19 cells was made and treated with basil polysaccharide for 50 d,the changes of the tumor cell biology phenotype were observed. 方法:建立荷NuTu-19卵巢癌大鼠模型及相应对照,观察中药罗勒多糖对荷瘤鼠肿瘤生长及转移行为的影响;
- Objective: To investigate the effect of hypoxia on the mRNA expression of tissue inhibitor of metalloproteinases (TIMPs) in breast carcinoma cell line (MDA-231) and the effect of basil polysaccharide (BP) on the expression of TIMPs. 目的:探讨低氧对人乳腺癌细胞株MDA-231金属蛋白酶组织抑制剂(TIMPs)mRNA表达的影响,以及罗勒多糖(basilpolysaccharide,BP)对TIMPs的作用。
- Compared with the control,the amounts of ascites of the rat treated with basil polysaccharide were decreased(P<0.05) and the score of abdominal carcinoma metastasis degree was decreased significantly (P<0.01). 与对照组相比;罗勒多糖治疗组肿瘤的生长及转移行为都受到明显的抑制:肿瘤数量减少;体积减小;腹水量显著减少(P<0.;05); 腹腔脏器转移程度积分显著降低(P<0
- Effect of basil polysaccharide on rat model bearing NuTu-19 cells 罗勒多糖对荷NuTu-19卵巢癌大鼠模型的作用研究
- Keywords basil polysaccharide;tumor metastases;GJIC;NK; 罗勒多糖;肿瘤转移;细胞间通讯;NK细胞;
- The Effects of Basil Polysaccharide on the Behavior of Tumor Metastasis 罗勒多糖对肿瘤转移行为的影响
- Keywords basil polysaccharide;anti-tumor metastasis;hypoxia;osteopontin; 罗勒多糖;抗肿瘤转移;乏氧;骨桥蛋白;
- The effect and mechanism analysis of basil polysaccharide against ovarian cancer 罗勒多糖对卵巢癌生物学行为的影响及其机制研究
- Experimental Research on the Anti-tumor-metastasis Action of Basil Polysaccharide in Vitro 罗勒多糖对肿瘤细胞侵袭转移活性的影响
- I see that Basil is in one of his sulky moods. 我觉得贝西尔现在情绪很低沉。
- Sir Basil Hunter refused his plastic dinner. 巴丝尔·享特爵士拒绝食用似是而非的晚餐。
- Basil was chivvying his awkward sister. 巴兹尔大声招呼着他难以对付的姐姐。
