Benzylisoquinoline compounds antagonize calmodulin (CaM) and inhibit the activity of cyclic nucleotide phosphodiesterase which is CaM-dependent (CaM-PDE) .

• 苄基异喹啉类化合物拮抗钙调素(CaM)并抑制依赖CaM的环核苷酸磷酸二酯酶(CaM-PDE)的活力;