Berberine, the major active constituent of Rhizoma coptidis, has a blood lipid lowering function. This paper reviews the research advance on molecule mechanism, animal experiment and clinical effect of berberine.

• 小檗碱是中药黄连的主要成分,具有降血脂的功能。现对小檗碱降血脂的分子机制、动物实验及临床疗效的研究进展作一综述。