Bilirubin may be overproduced or inadequately removed by the liver or leak into the Bloodstream after removal; jaundice may also be due to impaired Bile flow.

• 胆红素可能因肝脏分泌过多或未能完全清除,或清除后又大量反流入血(回流性黄疸),或直接从受损的胆管反流入血(阻塞性黄疸)。