By disrupting the stratum corneum structure and create pathways allowing transport of macromolecules, microneedles array can improve the transdermal drug delivery and increase the efficiency.

• 传统的被动式经皮给药严重受限于皮肤角质层的阻碍,利用微针阵列破坏角质层可改善皮肤对药物的渗透性,大大提高经皮给药效率。