By the thin layer chromatograph(TLC) and high pressure and liquid chromatograph(HPLC), 2strains with high ratio of Bla components were obtained. The liter of strain HY365 reached to 5924.67 ? g/mL and Bla component was 3892 ?

• 同时，用薄层层析法和H尸LC法筛选Bla组分较高菌株，最终得到组分优化的高效菌株2株，其中菌株卜IY365的总效价为5924.；67 pg/mL，它的Bla含量为3892“g/mL，占总效价的比例达到65