CCN genes are cysteine-rich conserved regulatory protein family with highly sequence homology. They play roles in cell proliferation, differentiation, embryo formation and wound healing, and have been reported to express abnormally in certain tumors.

• CCN基因家族是一类富含半胱氨酸的保守的调节蛋白家族，其成员具有极其显著的序列同源性，它们与调节细胞的增殖、分化、胚胎形成和伤口愈合等有关，且被报道在数种肿瘤中异常表达。