CONCLUSION DDP resistant L1210 subline is a good experimental model in vitro for the study of mechanism of antitumor-drug resistance and the screening of antitumor drug.

• 结论DDP耐药性L1210细胞亚系的建立，为深入研究肿瘤细胞耐药机制、寻找逆转耐药的措施提供了较好的体外实验模型。