CONCLUSION This study indicated that CK19mRNA is a potential marker for laryngeal and laryngopharyngeal carcinoma. DTC detection in peripheral blood by our meticulously designed RT-PCRsystem may be able to find the early metastasis event.

• 结论以CK19mRNA肿瘤标记物,用精确设计的RT-PCR技术对外周血DTC的检测有助于喉癌、喉咽癌转移的早期发现;