Cefixime open side chain acid was prepared by oximation,etherification,chlorination,ester decomposition using t-butyl acetoacetate as starting material.
英
美
- 以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。