Clonidine is an excellent drug but has side effects such as fatigue, sleepiness, and dry month that make it a second or third line choice.

• 可乐宁（又叫氯压定，可乐亭）对于高血压的效果非常好，但是存在导致肥胖，嗜睡和口干的副作用，所以也不能作为药物的首选。