Conclusion A kind of simple and speedy animal atherosclerostic model can be established by injecting with vitamine D3 and administering with nicotin based on high fat diet.

• 结论高脂饮食辅以维生素D3肌注和尼古丁灌胃是一种简单快速的大鼠动脉粥样硬化模型的复制方法。