Conclusion The formulation of DAL slow release tablet is optimal .The release in vitro showed no obvious difference between DAL and the controlled tablets .

• 结论:经正交设计优化的双氯芬酸赖氨酸盐缓释片处方为最优处方，体外释放与进口双氯芬酸钠缓释片相比无显著性差异。