Conclusion The results suggest that antitumor effect of SarCNU in EMT positive tumor is satisfactory even though the tumor exhibits DNA repair gene expression, specifically MGMT and ERCC1-6.

• 肿瘤细胞的EMT和DNA修复基因MGMT以及ERCC1 6的表达均为阳性。 结论 在EMT阳性的肿瘤 ,即使具有DNA修复基因表达 ,SarCNU仍然具有良好的抗肿瘤作用