Conclusions MTS1 gene was associated with the progression and proliferation in prostatic hyperplasia and homozygous deletion was one of the major inactivation mechanisms of MTS1 gene in BPH.

• 结论BPH的发病机制可能与MTS1的纯合性缺失有关，未见有突变发生。应对MTS1基因在人BPH中的作用作更深入的研究。