Conclusions: The changes of 5-HT and SERT in mice colonic mucosa are the results of DSS-induced colitis. 5-HT and SERT may be involved in the pathophysiological mechanisms of UC.

• 结论：DSS诱导的结肠炎促使小鼠结肠黏膜中5-HT含量和SERT的表达发生变化，5-HT和SERT可能参与了UC发生的病理生理机制。