Cyclin D3 is found to play a crucial role not only in progression through the G1 phase as a regulatory subunit of CDK 4 and CDK 6, but also in many other aspects, such as cell growth, cell differentiation, transcriptional regulation and apoptosis.

• 在cyclin D中,cyclin D3不仅作为一个CDK4和CDK6的调节亚基在G1期调节细胞周期进程,还与细胞生长、细胞分化、转录调节和凋亡有关。