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- There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways. 有很多原因可以解释,包括:乏氧驱使基因组不稳定性及改变DNA损伤修复通路的能力。
- This study has great importance in explaining the repair process of cell damage and provides new evidence of PARP in DNA damage repair process. 本研究可能对于理解电离辐射后细胞损伤修复过程具有重要意义,也为理解PARP在DNA损伤修复过程中发挥的作用提供新的证据。
- Poly(ADP-ribose)polymerases(PARP) is one of the most important enzymes in human body.It plays an vital role in chromatin relaxation, signal transduction, DNA damage repair and apoptosis. 聚腺苷二磷酸核糖聚合酶(PARP)是人体重要的酶之一,参与染色质松弛、信号转录、DNA修复和细胞凋亡等生理过程。
- Cell responses to ionizing radiation are determined by extent and repair capability of DNA damage.Capability of DNA damage repair and character of damage vary as a function of cell cycle. 细胞对电离辐射的反应取决于DNA的损伤程度及细胞对此损伤的修复能力,损伤后修复能力和损伤性质因细胞周期而异。
- The researches on functions of X ray repair cross complementing(XRCC) genes had promoted the understanding of DNA damage repair processes and the mechanism of cancer induced by genetic instability. 对X射线修复交叉互补(XRCC)基因功能的研究极大地促进了对哺乳动物DNA损伤修复过程和遗传不稳定性致癌机制的理解。
- Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods were used to measure DNA damage repair gene XPC and folate metabolism enzyme gene MTHFR polymorphisms. 对照组选自同期居住在扬中境内的居民,与病例按性别和年龄组进行成组频数匹配,要求身体健康,无恶性肿瘤及胃和十二指肠溃疡病史,征得同意后采集静脉血并进行流行病学问卷调查。
- DNA Damage Repair Gene and Genetic Susceptibility DNA损伤修复基因与遗传易感性
- Study of P53 and DNA damage repair P53与DNA损伤修复研究
- Keywords multiple myeloma;apurinic/apyrimidinic endonuclease;DNA damage repair; 多发性骨髓瘤;脱嘌呤/脱嘧啶核酸内切酶;DNA损伤修复;
- THE EFFECTS OF THE ENRICHED URANIUM OXYFLUORIDE ON DNA DAMAGE REPAIR IN MOUSE LYMPHOCYTES IN VIVO 浓缩铀内污染对小鼠脾淋巴细胞DNA损伤修复的作用
- Keywords Ataxia telangiectasia mutated;Breast cancer gene 1;DNA damage repair protein 51;Phosphorylation; 毛细血管扩张性共济失调突变基因;乳癌基因1;DNA修复相关蛋白;磷酸化;
- Keywords radiation;low dose hyper-radiosensitivity;DNA damage repair;cell cycle arrest; 辐射;低剂量辐射超敏感性;DNA损伤修复;细胞周期阻滞;
- Curbing DNA damage might make cancer less likely. 卷曲的DNA损伤导致癌症也很少。
- Catechins may also prevent DNA damage caused by carcinogens. 儿茶酚还可能预防致癌物质引起DNA损伤。
- DNA damage repair enzyme DNA损伤修复酶
- DNA damage repair protein 51 DNA修复相关蛋白
- GEN caused DNA damage but not due to oxidant effect. GEN导致细胞DNA断裂,但不是由其氧化效应引起。
- Both UV-A and UV-B irradiation induced DNA damage in mesophylls. 彗星检测结果表明,九里香叶片DNA的损伤程度与UV-B辐射的剂量呈正相关;
- DNA damage repair DNA损伤修复
- More and more studies show that the processes of DNA replication, damage repair and recombination are both independent and interdependent in the molecular level. DNA复制、损伤修复和重组过程的相互作用关系研究是当今生命科学研究的前沿和热点之一。