During antiviral drug selection pressure (e.g., lamivudine, adefovir, or entecavir) HBV mutants are selected from the pre-existing pool of quasispecies and over time become the dominant species.

• 在抗病毒药物的选择压力下（如拉米夫定、阿德福韦、恩替卡韦等），HBV突变株从之前存在的准种中经过选择，随着时间的推移而变成优势种。