Each SJL mouse was injected s. c. in the abdominal wall with PLP139-151, Mycobacteria H37RA and CFA, and Bordetella pertussis bacilli.

• 材料和方法:1、应用PLP139-151抗原、福氏佐剂和结核杆菌腹部皮下注射雌性SJL/J小鼠,并且尾静脉注射百日咳杆菌,诱发EAE小鼠动物模型,在免疫后观察60天,每天进行称重和行为学评分。