FK506 treatment can greatly improve the proteinuria and hyperlipidemia. Conversion from CsA to FK506 is an effective and safe alternative therapy for delaying the progression of renal dysfunction induced by CAN.

• FK506转换治疗后,肾功能减退得到延缓,蛋白尿降低,血脂代谢得到改善,FK506可以有效延缓CAN进展。