Features, mechanism, biological roles, and application of PTGS were reviewed and the feasibility of utilizing the mechanism to develop virus-resistant transgenic tobaccos was discussed.

• 对转录后基因沉默的特点和发生机制、PTGS与植物病毒抗性等方面进行综述,并在此基础上,就该技术策略应用于烟草抗病毒育种上的可行性进行探讨,并提出相关建议。