Fluoroalkyl acetic acids were converted to their corresponding carbonyl chlorides, which was then reacted with o-amino benzaldehyde and ammonia gas to give 3-(1-iminofluoroalkyl)-1H-qunolin-2-ones in moderate yields.

• 摘要用2-氟烷基乙酸为初始原料，用氯化亚砜或五氯化磷将其转化为相应的酰氯，后者在室温与邻胺基苯甲醛缩合，通入氨气回流反应得到3-（1-亚胺基氟烷基）－1H-喹啉－2-酮类化合物，产率中等。