Gastric hypersensitivity exists in a portion of FD patients,and is associated with an increase in number and degranulation of 5-HT-positive cells in proximal gastric mucosa.

• 部分FD患者存在胃感觉过敏,与近端胃黏膜5-HT阳性细胞数量增多、介质释放增加有关。