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The gene silence of XAF1 is related with the hypermethylation of its promotor. XAF1的基因沉默与其启动子高甲基化明显相关。
RNA interference has been taken as a powerful "gene silence" method widely used in basic science to study the function of genes, and it may lead to novel therapies in the future. 它已被作为一种强大的“基因沉默”技术被用于全球的实验室，而且，会推动新的医疗技术的出现。
With the widely application of transgene technology in the fields of high level biologies, more and more attention was payed to gene silence. 随着转基因技术在高等生物中的广泛应用,转基因沉默受到越来越多的重视。
RNA interference(RNAi) is a powerful gene tool targeting post-tra- -nscriptional gene silencing, which has recently been used to silence gene expression in various species. RNA干扰(RNAi)是一种转录后基因沉默(Post-transcriptional gene silence,PTGS)的基因阻断技术,近年来被广泛应用于哺乳动物细胞抑制基因表达。
Our data show that 5 aza CdR may inhibit tumor growth by reactivating growth regulatory genes silenced by de novo methylation. 5 aza CdR有肯定的抑瘤作用 ,其抑瘤作用的可能机理主要是通过p16基因去甲基化解除转录抑制完成的。
The mechanisms of gene silencing include copy numbers and configuration of transgene, integration sites in plant and transcription of transgene, etc. 基因沉默的机制是多方面的，包括转基因的拷贝数和构型、在植物上的整合位点、转基因的转录水平等。
Abstract: BACKGROUND: Gene promoter methylation is an epigenetic eent leading to gene silencing. 摘要：背景：基因启动子甲基化是一种可引起基因沉默的表观遗传事件。
Gene silencing can be divided into two types: position effect and homology dependent gene silencing (HdGS). 基因沉默大体可以分为两类：位置效应引起的基因沉默和同源依赖的基因沉默。
Gene silencing is a kind of epigenetic phenomenon discovered in transgenic plants in recent years. 摘要基因沉默是近几年来在转基因植物中发现的一种后生遗传现象。
Studying the cause for silencing of foreign genes and learning the method to overcome gene silencing are important for the development of plant gene engineering. 研究外源基因的失活原因及寻找相应的策略控制失活，对于植物基因工程的发展有著重要的意义。
Finally, the researchers showed that DNMT1-stimulated HP1 binding is required for gene silencing. 最后，研究者指出DNMT1激发性Hp1蛋白的结合作用需要基因沉默。
Posttranscriptional gene silencing(PTGS) is considered to be one of dominant mechanisms of RNA-mediated resistance. 转录后基因沉默现象是植物抵御病毒入侵、保持自身基因组完整性的一种防御机制。
RNA interference (RNAi) is a postranscriptional gene silencing (PTGS) mechanism induced by double-stranded RNA (dsRNA). 摘要RNA干扰，是1种由双链RNA引发的转录后基因沉默现象。
This mutant showed an increased sensitivity to DNA damage and release of transcriptional gene silencing (TGS) in heterochromatin. 这个突变体同时也显现了对DNA损伤的高敏感性以及在异染色质上转录基因沉默(TGS)的释放。
Abstract:Objective:To observe the effect of PKB gene silencing on the growth of gastric cancer cell line SGC-7901 in vitro. 目的:探讨蛋白激酶B（PKB）基因沉默对人胃癌SGC-7901细胞增殖的作用。
Posttranscriptional gene silencing (PTGS) in plants is a form of RNA silencing by which target RNA is degraded in a sequence-specific manner. 植物中的转录后基因沉默(PTGS)是RNA沉默的一种形式，通过PTGS能对目标RNA进行特异性降解。
From long period evolution with plants, plant virus obtains the ability to code gene silencing suppressors against this defense system. 基因沉默系统是植物抵抗病毒侵染的防卫体系，在长期的协同进化过程中，由病毒编码的抑制蛋白可以抵消基因沉默系统的作用。
TMV CP;different constructs;methylation;post transcriptional gene silencing;watermelon;virus diseases;transformation;resistance. 不同结构形式;甲基化;转录后基因沉默;西瓜病毒病;转基因;抗病性
SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing. Su(var)3-9家族的SDP专一甲基化组蛋白3第9位赖氨酸(H3K9),从而导致基因沉默(gene silencing)。
Transgenic plants with high and stable expression are ideal to get by plant gene engineering, but gene silencing limits their application. 摘要植物基因工程研究是希望获得高稳定表达的转基因植株，而转基因沉默现象却限制了转基因植物的应用前景。