HC may induce fibrogenesis directly by hepatic stellate cell actiation or indirectly by promoting oxidatie stress and apoptosis of infected cells.

• 慢性丙型肝炎可能通过肝脏星形胶质细胞的活化、或者间接通过促进氧化应激和受感染细胞的凋亡，直接诱导纤维形成。